We have a Min-Pin named Odie - Complete with the Garfield comic strip dog's ears and jumpin ability. When our beloved fellow was a pup he contracted Demodectic Mange. My vet informed me that years ago this was a death sentence for the little guys. However, Odie was treated with ivermectin 1% injectable solution purchased from the local feed store for $ for a 100 ml bottle. We had to give him doses of it daily. I can't recall the exact dosage our vet prescribed but it it was it was at least 1/2 a ML and since we gave it to him Daily it amounted to quite a bit of the stuff. it took a couple of months but his Demodectic mange went away and today he is a healthy and Happy member of our family. We are now giving ivermectin to our dogs rahter than purchasing Heartgard at the ungodly prices with the full blessing of our vet who cares more about animals than the bottom line.